Lowest Priced Flights from Panama from 348 USD!
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Search Top Routes and Airfare Deals from Panama
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USD
Panama City (PTY)to
Madrid (MAD)20/11/2025 - 30/11/2025
From
348Â USD
Viewed 43 minutes ago
Round trip
Economy
Panama City (PTY)to
Bilbao (BIO)13/11/2025 - 23/11/2025
From
687Â USD
Viewed 23 hours ago
Round trip
Economy
Panama City (PTY)to
Barcelona (BCN)19/10/2025 - 21/11/2025
From
696Â USD
Viewed 14 hours ago
Round trip
Economy
Panama City (PTY)to
Alicante (ALC)15/10/2025 - 21/10/2025
From
713Â USD
Viewed 1 minute ago
Round trip
Economy
Panama City (PTY)to
Milan (MXP)08/11/2025 - 15/11/2025
From
737Â USD
Viewed 17 hours ago
Round trip
Economy
Panama City (PTY)to
Amsterdam (AMS)16/11/2025 - 23/11/2025
From
769Â USD
Viewed 10 hours ago
Round trip
Economy
Panama City (PTY)to
Paris (ORY)17/10/2025 - 05/11/2025
From
796Â USD
Viewed 14 hours ago
Round trip
Economy
Panama City (PTY)to
Brussels (BRU)19/10/2025 - 26/10/2025
From
859Â USD
Viewed 17 hours ago
Round trip
Economy
Panama City (PTY)to
London (LGW)25/10/2025 - 01/11/2025
From
859Â USD
Viewed 15 hours ago
Round trip
Economy
Panama City (PTY)to
Zurich (ZRH)17/05/2026 - 24/05/2026
From
889Â USD
Viewed 19 hours ago
Round trip
Economy
Panama City (PTY)to
Vigo (VGO)28/11/2025 - 15/01/2026
From
914Â USD
Viewed 21 hours ago
Round trip
Economy
Panama City (PTY)to
Frankfurt (FRA)14/11/2025 - 26/11/2025
From
987Â USD
Viewed 3 hours ago
Round trip
Economy
Panama City (PTY)to
Valencia (VLC)08/10/2025 - 03/11/2025
From
1.006Â USD
Viewed 6 hours ago
Round trip
Economy
Panama City (PTY)to
Lisbon (LIS)16/01/2026 - 27/01/2026
From
1.065Â USD
Viewed 14 hours ago
Round trip
Economy
Panama City (PTY)to
Munich (MUC)16/02/2026 - 27/02/2026
From
1.067Â USD
Viewed 16 hours ago
Round trip
Economy
Panama City (PTY)to
Tel Aviv (TLV)14/02/2026 - 19/02/2026
From
1.071Â USD
Viewed 11 hours ago
Round trip
Economy
Panama City (PTY)to
Palma de Mallorca (PMI)25/09/2025 - 07/10/2025
From
1.071Â USD
Viewed 19 hours ago
Round trip
Economy
Panama City (PTY)to
Malaga (AGP)18/09/2025 - 26/09/2025
From
1.211Â USD
Viewed 23 hours ago
Round trip
Economy
Panama City (PTY)to
Porto (OPO)13/09/2025 - 27/09/2025
From
1.296Â USD
Viewed 20 hours ago
Round trip
Economy
Panama City (PTY)to
Istanbul (IST)14/09/2025 - 20/09/2025
From
1.589Â USD
Viewed 16 hours ago
Round trip
Economy
*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.
Search Top Routes and Airfare Deals from Panama
flight_takeoff
flight_land
USD
From | To | Trip type | Dates | Price |
|---|---|---|---|---|
| Panama City (PTY) | Madrid (MAD) | Round trip | Economy | 20/11/2025 - 30/11/2025 | From 348Â USD Viewed 43 minutes ago |
| Panama City (PTY) | Madrid (MAD) | Round trip | Economy | 14/11/2025 - 12/12/2025 | From 647Â USD Viewed 12 hours ago |
| Panama City (PTY) | Bilbao (BIO) | Round trip | Economy | 13/11/2025 - 23/11/2025 | From 687Â USD Viewed 23 hours ago |
| Panama City (PTY) | Barcelona (BCN) | Round trip | Economy | 19/10/2025 - 21/11/2025 | From 696Â USD Viewed 14 hours ago |
| Panama City (PTY) | Alicante (ALC) | Round trip | Economy | 15/10/2025 - 21/10/2025 | From 713Â USD Viewed 1 minute ago |
| Panama City (PTY) | Barcelona (BCN) | Round trip | Economy | 04/11/2025 - 20/11/2025 | From 732Â USD Viewed 1 hour ago |
| Panama City (PTY) | Milan (MXP) | Round trip | Economy | 08/11/2025 - 15/11/2025 | From 737Â USD Viewed 17 hours ago |
| Panama City (PTY) | Amsterdam (AMS) | Round trip | Economy | 16/11/2025 - 23/11/2025 | From 769Â USD Viewed 10 hours ago |
| Panama City (PTY) | Paris (ORY) | Round trip | Economy | 17/10/2025 - 05/11/2025 | From 796Â USD Viewed 14 hours ago |
| Panama City (PTY) | Bilbao (BIO) | Round trip | Economy | 07/11/2025 - 18/11/2025 | From 846Â USD Viewed 23 hours ago |
| Panama City (PTY) | Brussels (BRU) | Round trip | Economy | 19/10/2025 - 26/10/2025 | From 859Â USD Viewed 17 hours ago |
| Panama City (PTY) | London (LGW) | Round trip | Economy | 25/10/2025 - 01/11/2025 | From 859Â USD Viewed 15 hours ago |
| Panama City (PTY) | Zurich (ZRH) | Round trip | Economy | 17/05/2026 - 24/05/2026 | From 889Â USD Viewed 19 hours ago |
| Panama City (PTY) | Vigo (VGO) | Round trip | Economy | 28/11/2025 - 15/01/2026 | From 914Â USD Viewed 21 hours ago |
| Panama City (PTY) | Milan (MXP) | Round trip | Economy | 20/10/2025 - 03/11/2025 | From 927Â USD Viewed 1 minute ago |
| Panama City (PTY) | Amsterdam (AMS) | Round trip | Economy | 18/02/2026 - 10/03/2026 | From 932Â USD Viewed 8 hours ago |
| Panama City (PTY) | Frankfurt (FRA) | Round trip | Economy | 14/11/2025 - 26/11/2025 | From 987Â USD Viewed 3 hours ago |
| Panama City (PTY) | Valencia (VLC) | Round trip | Economy | 08/10/2025 - 03/11/2025 | From 1.006Â USD Viewed 6 hours ago |
| Panama City (PTY) | London (LGW) | Round trip | Economy | 02/02/2026 - 20/02/2026 | From 1.036Â USD Viewed 22 hours ago |
| Panama City (PTY) | Paris (ORY) | Round trip | Economy | 26/01/2026 - 12/02/2026 | From 1.061Â USD Viewed 10 hours ago |
*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.
Departing from Panama
Fly from Panama with Air Europa and get the best deal on your flight when you book through our official website. We offer flights to over 100 destinations around the world, including destinations in Europe and the Americas. Book your flight from Panama with Air Europa today and use our in-flight Wi-Fi to keep in touch with your friends and family.
Flights from Panama with Air Europa
Air Europa serves Panama via Panama City’s Tocumen International Airport (PTY), which lies 12.5 mi (20.2 km) north-east of the city centre. Call a taxi or book a ride on the shuttle to travel between the city centre and the airport. Travel time is 20 to 40 minutes, depending on the traffic.
- If you’ve squeezed in one last adventure before heading to the airport, stop by one of the airport lounges to enjoy a refreshing shower before your flight.
- Visit the currency exchange and ATM.
- Find last-minute souvenirs at the duty-free shops.
- Replenish your toiletries and medications at the pharmacy.
Earn miles and get special promotions when you join our Air Europa SUMA loyalty programme. Book your flight from Panama with Air Europa today and fly in comfort with our friendly staff.