Lowest Priced Flights from Panama from 796 USD!

Search Top Routes and Airfare Deals from Panama

USD

Panama City (PTY)to

Madrid (MAD)
18/02/2027 - 27/02/2027

Round trip

Economy

From
812 USD
Viewed 55 minutes ago

Panama City (PTY)to

Bilbao (BIO)
22/09/2026 - 28/09/2026

Round trip

Economy

From
830 USD
Viewed 18 hours ago

Panama City (PTY)to

Lisbon (LIS)
22/06/2026 - 18/09/2026

Round trip

Economy

From
887 USD
Viewed 2 hours ago

Panama City (PTY)to

Vigo (VGO)
02/07/2026 - 21/08/2026

Round trip

Economy

From
893 USD
Viewed 19 hours ago

Panama City (PTY)to

Malaga (AGP)
26/07/2026 - 30/08/2026

Round trip

Economy

From
962 USD
Viewed 12 hours ago

Panama City (PTY)to

Barcelona (BCN)
18/10/2026 - 27/10/2026

Round trip

Economy

From
1.007 USD
Viewed 2 hours ago

Panama City (PTY)to

Paris (ORY)
07/10/2026 - 13/10/2026

Round trip

Economy

From
1.012 USD
Viewed 23 hours ago

Panama City (PTY)to

Zurich (ZRH)
28/11/2026 - 23/04/2027

Round trip

Economy

From
1.253 USD
Viewed 17 hours ago

Panama City (PTY)to

Milan (MXP)
18/07/2026 - 29/07/2026

Round trip

Economy

From
1.352 USD
Viewed 16 hours ago

Panama City (PTY)to

Frankfurt (FRA)
22/08/2026 - 30/08/2026

Round trip

Economy

From
1.485 USD
Viewed 16 hours ago

*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.

Departing from Panama

Fly from Panama with Air Europa and get the best deal on your flight when you book through our official website. We offer flights to over 100 destinations around the world, including destinations in Europe and the Americas. Book your flight from Panama with Air Europa today and use our in-flight Wi-Fi to keep in touch with your friends and family.

Flights from Panama with Air Europa

Air Europa serves Panama via Panama City’s Tocumen International Airport (PTY), which lies 12.5 mi (20.2 km) north-east of the city centre. Call a taxi or book a ride on the shuttle to travel between the city centre and the airport. Travel time is 20 to 40 minutes, depending on the traffic.

  • If you’ve squeezed in one last adventure before heading to the airport, stop by one of the airport lounges to enjoy a refreshing shower before your flight.
  • Visit the currency exchange and ATM.
  • Find last-minute souvenirs at the duty-free shops.
  • Replenish your toiletries and medications at the pharmacy.

Earn miles and get special promotions when you join our Air Europa SUMA loyalty programme. Book your flight from Panama with Air Europa today and fly in comfort with our friendly staff.