Flights from Spain to Panama from 531 EUR
expand_more
1 Adult
expand_moretoday
today
Search Top Routes and Airfare Deals from Spain to Panama
flight_takeoff
flight_land
EUR
Madrid (MAD)to
Panama City (PTY)03/11/2026 - 13/11/2026
From
531Â EUR
Viewed 15 hours ago
Round trip
Economy
Barcelona (BCN)to
Panama City (PTY)20/10/2026 - 26/10/2026
From
562Â EUR
Viewed 3 hours ago
Round trip
Economy
Madrid (MAD)to
Panama City (PTY)20/10/2026 - 03/11/2026
From
563Â EUR
Viewed 5 hours ago
Round trip
Economy
Madrid (MAD)to
Panama City (PTY)11/10/2026 - 22/10/2026
From
563Â EUR
Viewed 4 hours ago
Round trip
Economy
Madrid (MAD)to
Panama City (PTY)15/10/2026 - 25/11/2026
From
563Â EUR
Viewed 4 hours ago
Round trip
Economy
Madrid (MAD)to
Panama City (PTY)24/10/2026 - 06/11/2026
From
563Â EUR
Viewed 19 hours ago
Round trip
Economy
Madrid (MAD)to
Panama City (PTY)23/10/2026 - 06/11/2026
From
563Â EUR
Viewed 14 hours ago
Round trip
Economy
Barcelona (BCN)to
Panama City (PTY)26/04/2027 - 28/04/2027
From
586Â EUR
Viewed 6 hours ago
Round trip
Economy
Barcelona (BCN)to
Panama City (PTY)26/04/2027 - 03/05/2027
From
586Â EUR
Viewed 6 hours ago
Round trip
Economy
Barcelona (BCN)to
Panama City (PTY)26/04/2027 - 12/05/2027
From
586Â EUR
Viewed 6 hours ago
Round trip
Economy
Barcelona (BCN)to
Panama City (PTY)26/04/2027 - 17/05/2027
From
586Â EUR
Viewed 6 hours ago
Round trip
Economy
Barcelona (BCN)to
Panama City (PTY)26/04/2027 - 18/05/2027
From
586Â EUR
Viewed 6 hours ago
Round trip
Economy
Vigo (VGO)to
Panama City (PTY)29/09/2026 - 03/11/2026
From
594Â EUR
Viewed 6 hours ago
Round trip
Economy
Vigo (VGO)to
Panama City (PTY)10/09/2026 - 09/10/2026
From
594Â EUR
Viewed 1 day ago
Round trip
Economy
Vigo (VGO)to
Panama City (PTY)11/09/2026 - 12/10/2026
From
594Â EUR
Viewed 6 minutes ago
Round trip
Economy
Valencia (VLC)to
Panama City (PTY)03/11/2026 - 09/11/2026
From
595Â EUR
Viewed 23 hours ago
Round trip
Economy
Malaga (AGP)to
Panama City (PTY)19/10/2026 - 18/11/2026
From
596Â EUR
Viewed 19 hours ago
Round trip
Economy
Malaga (AGP)to
Panama City (PTY)16/11/2026 - 26/11/2026
From
596Â EUR
Viewed 23 hours ago
Round trip
Economy
Alicante (ALC)to
Panama City (PTY)19/10/2026 - 03/11/2026
From
596Â EUR
Viewed 1 day ago
Round trip
Economy
Alicante (ALC)to
Panama City (PTY)30/09/2026 - 09/11/2026
From
596Â EUR
Viewed 1 day ago
Round trip
Economy
*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.
Thinking about a vacation??
The best flight + hotel deals, tours and more just one click away.