Lowest Priced Flights from Panama City from 742 USD!
expand_more
1 Adult
expand_moretoday
today
Search Top Routes and Airfare Deals from Panama City
flight_takeoff
flight_land
USD
Panama City (PTY)to
Madrid (MAD)
19/05/2026 - 22/05/2026
Round trip
Economy
From
742Â USD
Viewed 16 hours ago
Panama City (PTY)to
Barcelona (BCN)
01/03/2027 - 06/03/2027
Round trip
Economy
From
797Â USD
Viewed 5 hours ago
Panama City (PTY)to
Lisbon (LIS)
19/11/2026 - 30/11/2026
Round trip
Economy
From
809Â USD
Viewed 17 hours ago
Panama City (PTY)to
Brussels (BRU)
16/11/2026 - 30/11/2026
Round trip
Economy
From
829Â USD
Viewed 12 hours ago
Panama City (PTY)to
Bilbao (BIO)
22/10/2026 - 29/10/2026
Round trip
Economy
From
862Â USD
Viewed 12 hours ago
Panama City (PTY)to
Vigo (VGO)
24/05/2026 - 31/05/2026
Round trip
Economy
From
898Â USD
Viewed 14 hours ago
Panama City (PTY)to
Valencia (VLC)
05/05/2026 - 10/05/2026
Round trip
Economy
From
905Â USD
Viewed 15 hours ago
Panama City (PTY)to
Frankfurt (FRA)
19/06/2026 - 17/09/2026
Round trip
Economy
From
921Â USD
Viewed 21 hours ago
Panama City (PTY)to
Milan (MXP)
09/05/2026 - 26/05/2026
Round trip
Economy
From
930Â USD
Viewed 17 hours ago
Panama City (PTY)to
London (LGW)
01/06/2026 - 07/06/2026
Round trip
Economy
From
1.112Â USD
Viewed 13 hours ago
*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.