Lowest Priced Flights from Panama City from 725 USD!
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Search Top Routes and Airfare Deals from Panama City
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USD
Panama City (PTY)to
Madrid (MAD)10/01/2026 - 10/22/2026
From
725Â USD
Viewed 20 hours ago
Round trip
Economy
Panama City (PTY)to
Alicante (ALC)05/18/2026 - 05/29/2026
From
743Â USD
Viewed 9 hours ago
Round trip
Economy
Panama City (PTY)to
Valencia (VLC)05/04/2026 - 05/10/2026
From
744Â USD
Viewed 2 hours ago
Round trip
Economy
Panama City (PTY)to
Venice (VCE)09/28/2026 - 10/11/2026
From
766Â USD
Viewed 8 hours ago
Round trip
Economy
Panama City (PTY)to
Barcelona (BCN)05/30/2026 - 06/08/2026
From
786Â USD
Viewed 2 hours ago
Round trip
Economy
Panama City (PTY)to
Milan (MXP)06/03/2026 - 06/09/2026
From
798Â USD
Viewed 9 hours ago
Round trip
Economy
Panama City (PTY)to
Bilbao (BIO)04/21/2026 - 04/28/2026
From
807Â USD
Viewed 9 hours ago
Round trip
Economy
Panama City (PTY)to
Palma de Mallorca (PMI)01/28/2026 - 02/05/2026
From
840Â USD
Viewed 10 hours ago
Round trip
Economy
Panama City (PTY)to
Malaga (AGP)01/28/2026 - 02/05/2026
From
845Â USD
Viewed 10 hours ago
Round trip
Economy
Panama City (PTY)to
Paris (ORY)02/19/2026 - 02/24/2026
From
890Â USD
Viewed 22 hours ago
Round trip
Economy
Panama City (PTY)to
Brussels (BRU)02/12/2026 - 02/22/2026
From
934Â USD
Viewed 5 hours ago
Round trip
Economy
Panama City (PTY)to
London (LGW)04/28/2026 - 05/07/2026
From
979Â USD
Viewed 21 hours ago
Round trip
Economy
Panama City (PTY)to
Istanbul (IST)10/01/2026 - 10/29/2026
From
996Â USD
Viewed 3 hours ago
Round trip
Economy
Panama City (PTY)to
Lisbon (LIS)04/13/2026 - 05/12/2026
From
1.006Â USD
Viewed 3 hours ago
Round trip
Economy
Panama City (PTY)to
A Coruna (LCG)02/28/2026 - 03/16/2026
From
1.011Â USD
Viewed 19 hours ago
Round trip
Economy
Panama City (PTY)to
Zurich (ZRH)01/24/2026 - 02/08/2026
From
1.100Â USD
Viewed 22 hours ago
Round trip
Economy
Panama City (PTY)to
Vigo (VGO)12/30/2025 - 03/07/2026
From
1.107Â USD
Viewed 1 hour ago
Round trip
Economy
Panama City (PTY)to
Porto (OPO)12/28/2025 - 01/31/2026
From
1.195Â USD
Viewed 13 hours ago
Round trip
Economy
Panama City (PTY)to
Frankfurt (FRA)12/31/2025 - 01/12/2026
From
1.528Â USD
Viewed 12 hours ago
Round trip
Economy
Panama City (PTY)to
Paris (CDG)09/11/2026 - 09/27/2026
From
1.610Â USD
Viewed 11 hours ago
Round trip
Economy
*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.