Lowest Priced Flights from Panama from 644 USD!
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Search Top Routes and Airfare Deals from Panama
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USD
Panama City (PTY)to
Madrid (MAD)10/25/2025 - 11/07/2025
From
644Â USD
Viewed 17 hours ago
Round trip
Economy
Panama City (PTY)to
Alicante (ALC)10/15/2025 - 10/21/2025
From
715Â USD
Viewed 1 hour ago
Round trip
Economy
Panama City (PTY)to
Valencia (VLC)10/13/2025 - 11/20/2025
From
762Â USD
Viewed 16 hours ago
Round trip
Economy
Panama City (PTY)to
Tenerife (TFN)10/22/2025 - 10/27/2025
From
770Â USD
Viewed 18 hours ago
Round trip
Economy
Panama City (PTY)to
Vigo (VGO)11/25/2025 - 11/30/2025
From
858Â USD
Viewed 9 hours ago
Round trip
Economy
Panama City (PTY)to
Barcelona (BCN)10/22/2025 - 11/04/2025
From
900Â USD
Viewed 11 hours ago
Round trip
Economy
Panama City (PTY)to
A Coruna (LCG)04/10/2026 - 04/19/2026
From
919Â USD
Viewed 22 hours ago
Round trip
Economy
Panama City (PTY)to
Paris (ORY)02/10/2026 - 02/18/2026
From
922Â USD
Viewed 9 hours ago
Round trip
Economy
Panama City (PTY)to
Frankfurt (FRA)11/14/2025 - 11/25/2025
From
931Â USD
Viewed 2 hours ago
Round trip
Economy
Panama City (PTY)to
Porto (OPO)10/26/2025 - 11/08/2025
From
981Â USD
Viewed 20 hours ago
Round trip
Economy
Panama City (PTY)to
London (LGW)10/27/2025 - 11/05/2025
From
997Â USD
Viewed 4 hours ago
Round trip
Economy
Panama City (PTY)to
Lisbon (LIS)11/18/2025 - 11/30/2025
From
1.008Â USD
Viewed 8 hours ago
Round trip
Economy
Panama City (PTY)to
Istanbul (IST)02/03/2026 - 02/21/2026
From
1.033Â USD
Viewed 16 hours ago
Round trip
Economy
Panama City (PTY)to
Milan (MXP)12/15/2025 - 02/23/2026
From
1.155Â USD
Viewed 15 hours ago
Round trip
Economy
Panama City (PTY)to
Venice (VCE)12/29/2025 - 01/11/2026
From
1.155Â USD
Viewed 18 hours ago
Round trip
Economy
Panama City (PTY)to
Bilbao (BIO)10/07/2025 - 11/07/2025
From
1.176Â USD
Viewed 9 hours ago
Round trip
Economy
Panama City (PTY)to
Tel Aviv (TLV)12/07/2025 - 12/30/2025
From
1.377Â USD
Viewed 12 hours ago
Round trip
Economy
Panama City (PTY)to
Athens (ATH)09/16/2025 - 09/23/2025
From
1.607Â USD
Viewed 11 hours ago
Round trip
Economy
*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.
Search Top Routes and Airfare Deals from Panama
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USD
From | To | Trip type | Dates | Price |
|---|---|---|---|---|
| Panama City (PTY) | Madrid (MAD) | Round trip | Economy | 10/25/2025 - 11/07/2025 | From 644Â USD Viewed 17 hours ago |
| Panama City (PTY) | Madrid (MAD) | Round trip | Economy | 10/27/2025 - 11/07/2025 | From 644Â USD Viewed 17 hours ago |
| Panama City (PTY) | Alicante (ALC) | Round trip | Economy | 10/15/2025 - 10/21/2025 | From 715Â USD Viewed 1 hour ago |
| Panama City (PTY) | Valencia (VLC) | Round trip | Economy | 10/13/2025 - 11/20/2025 | From 762Â USD Viewed 16 hours ago |
| Panama City (PTY) | Tenerife (TFN) | Round trip | Economy | 10/22/2025 - 10/27/2025 | From 770Â USD Viewed 18 hours ago |
| Panama City (PTY) | Vigo (VGO) | Round trip | Economy | 11/25/2025 - 11/30/2025 | From 858Â USD Viewed 9 hours ago |
| Panama City (PTY) | Barcelona (BCN) | Round trip | Economy | 10/22/2025 - 11/04/2025 | From 900Â USD Viewed 11 hours ago |
| Panama City (PTY) | A Coruna (LCG) | Round trip | Economy | 04/10/2026 - 04/19/2026 | From 919Â USD Viewed 22 hours ago |
| Panama City (PTY) | Paris (ORY) | Round trip | Economy | 02/10/2026 - 02/18/2026 | From 922Â USD Viewed 9 hours ago |
| Panama City (PTY) | Paris (ORY) | Round trip | Economy | 11/16/2025 - 11/27/2025 | From 928Â USD Viewed 12 hours ago |
| Panama City (PTY) | Frankfurt (FRA) | Round trip | Economy | 11/14/2025 - 11/25/2025 | From 931Â USD Viewed 2 hours ago |
| Panama City (PTY) | Frankfurt (FRA) | Round trip | Economy | 05/16/2026 - 05/23/2026 | From 942Â USD Viewed 18 hours ago |
| Panama City (PTY) | Porto (OPO) | Round trip | Economy | 10/26/2025 - 11/08/2025 | From 981Â USD Viewed 20 hours ago |
| Panama City (PTY) | London (LGW) | Round trip | Economy | 10/27/2025 - 11/05/2025 | From 997Â USD Viewed 4 hours ago |
| Panama City (PTY) | Vigo (VGO) | Round trip | Economy | 12/25/2025 - 02/03/2026 | From 998Â USD Viewed 9 hours ago |
| Panama City (PTY) | Lisbon (LIS) | Round trip | Economy | 11/18/2025 - 11/30/2025 | From 1.008Â USD Viewed 8 hours ago |
| Panama City (PTY) | Tenerife (TFN) | Round trip | Economy | 01/20/2026 - 01/31/2026 | From 1.033Â USD Viewed 22 hours ago |
| Panama City (PTY) | Istanbul (IST) | Round trip | Economy | 02/03/2026 - 02/21/2026 | From 1.033Â USD Viewed 16 hours ago |
| Panama City (PTY) | A Coruna (LCG) | Round trip | Economy | 12/15/2025 - 01/15/2026 | From 1.035Â USD Viewed 22 hours ago |
| Panama City (PTY) | Barcelona (BCN) | Round trip | Economy | 12/17/2025 - 01/17/2026 | From 1.037Â USD Viewed 11 hours ago |
*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.
Departing from Panama
Fly from Panama with Air Europa and get the best deal on your flight when you book through our official website. We offer flights to over 100 destinations around the world, including destinations in Europe and the Americas. Book your flight from Panama with Air Europa today and use our in-flight Wi-Fi to keep in touch with your friends and family.
Flights from Panama with Air Europa
Air Europa serves Panama via Panama City’s Tocumen International Airport (PTY), which lies 12.5 mi (20.2 km) north-east of the city centre. Call a taxi or book a ride on the shuttle to travel between the city centre and the airport. Travel time is 20 to 40 minutes, depending on the traffic.
- If you’ve squeezed in one last adventure before heading to the airport, stop by one of the airport lounges to enjoy a refreshing shower before your flight.
- Visit the currency exchange and ATM.
- Find last-minute souvenirs at the duty-free shops.
- Replenish your toiletries and medications at the pharmacy.
Earn miles and get special promotions when you join our Air Europa SUMA loyalty programme. Book your flight from Panama with Air Europa today and fly in comfort with our friendly staff.