Lowest Priced Flights from Panama from 673 USD!

Search Top Routes and Airfare Deals from Panama

USD

Panama City (PTY)to

Madrid (MAD)
04/29/2026 - 05/05/2026
From
673 USD
Viewed 9 hours ago
Round trip
Economy

Panama City (PTY)to

Bilbao (BIO)
06/02/2026 - 06/23/2026
From
745 USD
Viewed 14 hours ago
Round trip
Economy

Panama City (PTY)to

Vigo (VGO)
08/04/2026 - 09/17/2026
From
745 USD
Viewed 22 hours ago
Round trip
Economy

Panama City (PTY)to

Malaga (AGP)
05/28/2026 - 06/07/2026
From
746 USD
Viewed 6 hours ago
Round trip
Economy

Panama City (PTY)to

Barcelona (BCN)
05/24/2026 - 06/14/2026
From
756 USD
Viewed 1 hour ago
Round trip
Economy

Panama City (PTY)to

Lisbon (LIS)
06/05/2026 - 06/09/2026
From
768 USD
Viewed 14 hours ago
Round trip
Economy

Panama City (PTY)to

Paris (ORY)
04/28/2026 - 05/19/2026
From
804 USD
Viewed 16 hours ago
Round trip
Economy

Panama City (PTY)to

A Coruna (LCG)
04/01/2026 - 04/15/2026
From
818 USD
Viewed 21 hours ago
Round trip
Economy

Panama City (PTY)to

Tenerife (TFN)
06/01/2026 - 06/16/2026
From
830 USD
Viewed 9 hours ago
Round trip
Economy

Panama City (PTY)to

Amsterdam (AMS)
06/06/2026 - 06/14/2026
From
838 USD
Viewed 23 hours ago
Round trip
Economy

Panama City (PTY)to

Frankfurt (FRA)
06/16/2026 - 06/23/2026
From
881 USD
Viewed 2 hours ago
Round trip
Economy

Panama City (PTY)to

Zurich (ZRH)
04/01/2026 - 04/15/2026
From
883 USD
Viewed 23 hours ago
Round trip
Economy

Panama City (PTY)to

Milan (MXP)
09/16/2026 - 09/28/2026
From
928 USD
Viewed 2 hours ago
Round trip
Economy

Panama City (PTY)to

Porto (OPO)
03/30/2026 - 05/09/2026
From
930 USD
Viewed 12 hours ago
Round trip
Economy

Panama City (PTY)to

Munich (MUC)
11/01/2026 - 11/15/2026
From
954 USD
Viewed 7 hours ago
Round trip
Economy

Panama City (PTY)to

Brussels (BRU)
04/30/2026 - 05/16/2026
From
960 USD
Viewed 19 minutes ago
Round trip
Economy

Panama City (PTY)to

Venice (VCE)
10/07/2026 - 10/18/2026
From
984 USD
Viewed 11 hours ago
Round trip
Economy

Panama City (PTY)to

London (LGW)
04/15/2026 - 04/22/2026
From
1.006 USD
Viewed 3 hours ago
Round trip
Economy

Panama City (PTY)to

Valencia (VLC)
03/18/2026 - 03/25/2026
From
1.050 USD
Viewed 7 hours ago
Round trip
Economy

Panama City (PTY)to

Palma de Mallorca (PMI)
07/18/2026 - 08/02/2026
From
1.069 USD
Viewed 5 hours ago
Round trip
Economy

*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.

Search and Book Lowest airfares from Panama

Departing from Panama

Fly from Panama with Air Europa and get the best deal on your flight when you book through our official website. We offer flights to over 100 destinations around the world, including destinations in Europe and the Americas. Book your flight from Panama with Air Europa today and use our in-flight Wi-Fi to keep in touch with your friends and family.

Flights from Panama with Air Europa

Air Europa serves Panama via Panama City’s Tocumen International Airport (PTY), which lies 12.5 mi (20.2 km) north-east of the city centre. Call a taxi or book a ride on the shuttle to travel between the city centre and the airport. Travel time is 20 to 40 minutes, depending on the traffic.

  • If you’ve squeezed in one last adventure before heading to the airport, stop by one of the airport lounges to enjoy a refreshing shower before your flight.
  • Visit the currency exchange and ATM.
  • Find last-minute souvenirs at the duty-free shops.
  • Replenish your toiletries and medications at the pharmacy.

Earn miles and get special promotions when you join our Air Europa SUMA loyalty programme. Book your flight from Panama with Air Europa today and fly in comfort with our friendly staff.