Air Europa's Lowest Priced Flights from Panama from 725 USD!

Search Top Routes and Airfare Deals from Panama

Panama City (PTY)to

Madrid (MAD)
09/30/2025 - 10/13/2025
From
725 USD
Viewed 1 hour ago
Round trip
Economy

Panama City (PTY)to

Barcelona (BCN)
11/16/2025 - 11/23/2025
From
754 USD
Viewed 1 hour ago
Round trip
Economy

Panama City (PTY)to

Milan (MXP)
05/08/2026 - 05/18/2026
From
764 USD
Viewed 1 hour ago
Round trip
Economy

Panama City (PTY)to

Marrakech (RAK)
05/02/2026 - 05/22/2026
From
766 USD
Viewed 7 hours ago
Round trip
Economy

Panama City (PTY)to

Porto (OPO)
04/30/2026 - 05/07/2026
From
790 USD
Viewed 8 hours ago
Round trip
Economy

Panama City (PTY)to

Malaga (AGP)
08/04/2025 - 08/25/2025
From
807 USD
Viewed 8 hours ago
Round trip
Economy

Panama City (PTY)to

Valencia (VLC)
09/12/2025 - 09/25/2025
From
808 USD
Viewed 23 hours ago
Round trip
Economy

Panama City (PTY)to

Lisbon (LIS)
08/07/2025 - 09/05/2025
From
831 USD
Viewed 3 hours ago
Round trip
Economy

Panama City (PTY)to

Venice (VCE)
02/16/2026 - 02/23/2026
From
832 USD
Viewed 3 hours ago
Round trip
Economy

Panama City (PTY)to

Vigo (VGO)
08/07/2025 - 08/21/2025
From
872 USD
Viewed 9 hours ago
Round trip
Economy

Panama City (PTY)to

Paris (ORY)
09/12/2025 - 09/20/2025
From
890 USD
Viewed 3 hours ago
Round trip
Economy

Panama City (PTY)to

Zurich (ZRH)
02/28/2026 - 03/14/2026
From
923 USD
Viewed 20 minutes ago
Round trip
Economy

Panama City (PTY)to

Istanbul (IST)
09/23/2025 - 10/18/2025
From
994 USD
Viewed 6 hours ago
Round trip
Economy

Panama City (PTY)to

London (LGW)
09/17/2025 - 09/21/2025
From
1.004 USD
Viewed 6 hours ago
Round trip
Economy

Panama City (PTY)to

Athens (ATH)
08/06/2025 - 08/17/2025
From
1.077 USD
Viewed 5 hours ago
Round trip
Economy

Panama City (PTY)to

Frankfurt (FRA)
11/16/2025 - 11/28/2025
From
1.083 USD
Viewed 16 hours ago
Round trip
Economy

Panama City (PTY)to

Tel Aviv (TLV)
08/09/2025 - 10/16/2025
From
1.237 USD
Viewed 8 hours ago
Round trip
Economy

Panama City (PTY)to

Amsterdam (AMS)
12/01/2025 - 12/21/2025
From
1.355 USD
Viewed 7 hours ago
Round trip
Economy

Panama City (PTY)to

Paris (CDG)
11/14/2025 - 11/30/2025
From
1.371 USD
Viewed 6 hours ago
Round trip
Economy

Panama City (PTY)to

A Coruna (LCG)
07/24/2025 - 08/05/2025
From
1.425 USD
Viewed 23 hours ago
Round trip
Economy

*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.

Search Top Routes and Airfare Deals from Panama

Search Top Routes and Airfare Deals from Panama
From
To
Trip type
Dates
Price
Panama City (PTY)Madrid (MAD)Round trip
|
Economy
06/16/2026 - 06/30/2026

From

725 USD

Viewed 21 hours ago

Panama City (PTY)Madrid (MAD)Round trip
|
Economy
09/30/2025 - 10/13/2025

From

725 USD

Viewed 1 hour ago

Panama City (PTY)Barcelona (BCN)Round trip
|
Economy
11/16/2025 - 11/23/2025

From

754 USD

Viewed 1 hour ago

Panama City (PTY)Milan (MXP)Round trip
|
Economy
05/08/2026 - 05/18/2026

From

764 USD

Viewed 1 hour ago

Panama City (PTY)Milan (MXP)Round trip
|
Economy
05/08/2026 - 05/19/2026

From

764 USD

Viewed 1 hour ago

Panama City (PTY)Marrakech (RAK)Round trip
|
Economy
05/02/2026 - 05/22/2026

From

766 USD

Viewed 7 hours ago

Panama City (PTY)Barcelona (BCN)Round trip
|
Economy
11/14/2025 - 11/23/2025

From

786 USD

Viewed 1 hour ago

Panama City (PTY)Porto (OPO)Round trip
|
Economy
04/30/2026 - 05/07/2026

From

790 USD

Viewed 8 hours ago

Panama City (PTY)Valencia (VLC)Round trip
|
Economy
09/12/2025 - 09/25/2025

From

808 USD

Viewed 23 hours ago

Panama City (PTY)Venice (VCE)Round trip
|
Economy
02/16/2026 - 02/23/2026

From

832 USD

Viewed 3 hours ago

Panama City (PTY)Malaga (AGP)Round trip
|
Economy
12/29/2025 - 02/25/2026

From

876 USD

Viewed 19 hours ago

Panama City (PTY)Paris (ORY)Round trip
|
Economy
09/12/2025 - 09/20/2025

From

890 USD

Viewed 3 hours ago

Panama City (PTY)Paris (ORY)Round trip
|
Economy
02/09/2026 - 03/15/2026

From

892 USD

Viewed 7 hours ago

Panama City (PTY)Lisbon (LIS)Round trip
|
Economy
01/21/2026 - 01/25/2026

From

901 USD

Viewed 10 hours ago

Panama City (PTY)Zurich (ZRH)Round trip
|
Economy
02/28/2026 - 03/14/2026

From

923 USD

Viewed 20 minutes ago

Panama City (PTY)Vigo (VGO)Round trip
|
Economy
10/03/2025 - 10/12/2025

From

951 USD

Viewed 7 hours ago

Panama City (PTY)Zurich (ZRH)Round trip
|
Economy
12/31/2025 - 01/30/2026

From

964 USD

Viewed 7 hours ago

Panama City (PTY)Venice (VCE)Round trip
|
Economy
11/29/2025 - 01/10/2026

From

981 USD

Viewed 1 hour ago

Panama City (PTY)Istanbul (IST)Round trip
|
Economy
09/23/2025 - 10/18/2025

From

994 USD

Viewed 6 hours ago

Panama City (PTY)Istanbul (IST)Round trip
|
Economy
05/14/2026 - 05/31/2026

From

996 USD

Viewed 9 hours ago

*Prices have been available for round-trip flights within the last 48 hours and may not be currently available. Additional baggage fees and fees for other optional services may apply. Other terms and conditions may apply.

Search and Book Lowest airfares from Panama

Departing from Panama

Fly from Panama with Air Europa and get the best deal on your flight when you book through our official website. We offer flights to over 100 destinations around the world, including destinations in Europe and the Americas. Book your flight from Panama with Air Europa today and use our in-flight Wi-Fi to keep in touch with your friends and family.

Flights from Panama with Air Europa

Air Europa serves Panama via Panama City’s Tocumen International Airport (PTY), which lies 12.5 mi (20.2 km) north-east of the city centre. Call a taxi or book a ride on the shuttle to travel between the city centre and the airport. Travel time is 20 to 40 minutes, depending on the traffic.

  • If you’ve squeezed in one last adventure before heading to the airport, stop by one of the airport lounges to enjoy a refreshing shower before your flight.
  • Visit the currency exchange and ATM.
  • Find last-minute souvenirs at the duty-free shops.
  • Replenish your toiletries and medications at the pharmacy.

Earn miles and get special promotions when you join our Air Europa SUMA loyalty programme. Book your flight from Panama with Air Europa today and fly in comfort with our friendly staff.